Oil encapsulation in core-shell alginate capsules by inverse gelation II: comparison between dripping techniques using W/O or O/W emulsions

J Microencapsul. 2017 Sep;34(6):522-534. doi: 10.1080/02652048.2017.1365963. Epub 2017 Aug 23.

Abstract

In the first part of this article, it was described an innovative method of oil encapsulation from dripping-inverse gelation using water-in-oil (W/O) emulsions. It was noticed that the method of oil encapsulation was quite different depending on the emulsion type (W/O or oil-in-water (O/W)) used and that the emulsion structure (W/O or O/W) had a high impact on the dripping technique and the capsules characteristics. The objective of this article was to elucidate the differences between the dripping techniques using both emulsions and compare the capsule properties (mechanical resistance and release of actives). The oil encapsulation using O/W emulsions was easier to perform and did not require the use of emulsion destabilisers. However, capsules produced from W/O emulsions were more resistant to compression and showed the slower release of actives over time. The findings detailed here widened the knowledge of the inverse gelation and gave opportunities to develop new techniques of oil encapsulation.

Keywords: Compression; cross-linking; emulsion; encapsulation; fluorescence spectroscopy; hydrogels.

Publication types

  • Comparative Study

MeSH terms

  • Alginates / chemistry*
  • Capsules*
  • Drug Liberation
  • Emulsions / chemistry*
  • Gels
  • Glucuronic Acid / chemistry
  • Hexuronic Acids / chemistry
  • Oils
  • Technology, Pharmaceutical*

Substances

  • Alginates
  • Capsules
  • Emulsions
  • Gels
  • Hexuronic Acids
  • Oils
  • Glucuronic Acid