Blends and Nanocomposite Biomaterials for Articular Cartilage Tissue Engineering

Azadehsadat Hashemi Doulabi; Kibret Mequanint; Hadi Mohammadi

doi:10.3390/ma7075327

Blends and Nanocomposite Biomaterials for Articular Cartilage Tissue Engineering

Materials (Basel). 2014 Jul 22;7(7):5327-5355. doi: 10.3390/ma7075327.

Authors

Azadehsadat Hashemi Doulabi¹, Kibret Mequanint^{2

3}, Hadi Mohammadi^{4

5}

Affiliations

¹ School of Engineering, Faculty of Applied Science, University of British Columbia, Kelowna, BC V1V 1V7, Canada. hashemi.azadeh@gmail.com.
² Department of Chemical and Biochemical Engineering, the University of Western Ontario, London, ON N6A 5B9, Canada. kmequani@uwo.ca.
³ Biomedical Engineering Graduate Program, the University of Western Ontario, London, ON N6A 5B9, Canada. kmequani@uwo.ca.
⁴ School of Engineering, Faculty of Applied Science, University of British Columbia, Kelowna, BC V1V 1V7, Canada. hadi.mohammadi@ubc.ca.
⁵ Biomedical Engineering Graduate Program, University of British Columbia, Vancouver, BC V6T 1Z4, Canada. hadi.mohammadi@ubc.ca.

Abstract

This review provides a comprehensive assessment on polymer blends and nanocomposite systems for articular cartilage tissue engineering applications. Classification of various types of blends including natural/natural, synthetic/synthetic systems, their combination and nanocomposite biomaterials are studied. Additionally, an inclusive study on their characteristics, cell responses ability to mimic tissue and regenerate damaged articular cartilage with respect to have functionality and composition needed for native tissue, are also provided.

Keywords: articular cartilage; biomaterial; blend; nanocomposite; tissue engineering.

Publication types

Review