Doege-potter syndrome: a report of a histologically benign but clinically malignant case

J Cardiothorac Surg. 2017 Aug 7;12(1):64. doi: 10.1186/s13019-017-0630-4.

Abstract

Background: Solitary fibrous tumors of the pleura (SFTPs) are relatively rare tumors that originate from mesenchymal cells of submesothelial tissue of the pleura. Most patients with SFTPs are asymptomatic; however, pleuritic chest pain, cough, and dyspnea can develop. If hypoglycemia is associated with a solitary fibrous tumor, it is referred to as the Doege-Potter syndrome.

Case presentation: A 70-year-old man had visited our hospital with a chief complaint of dyspnea, and he was diagnosed as having a solitary fibrous tumor. A few years later, he developed hypoglycemia, and he underwent excision of the mass.

Conclusion: Occasionally, SFTPs induce several paraneoplastic events, such as hypertrophic osteoarthropathy. We described here a patient with an SFTP with Doege-Potter syndrome who was successfully treated with complete resection. Although lesions can be histologically benign, they can clinically present with malignant features.

Keywords: Benign; Fibrous neoplasm; Pleural disease; Tumor.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Biopsy
  • Congenital Abnormalities / pathology*
  • Congenital Abnormalities / surgery
  • Diagnosis, Differential
  • Humans
  • Kidney / abnormalities*
  • Kidney / pathology
  • Kidney / surgery
  • Kidney Diseases / congenital*
  • Kidney Diseases / pathology
  • Kidney Diseases / surgery
  • Male
  • Pleura / pathology*
  • Pleura / surgery
  • Pleural Neoplasms / diagnosis*
  • Solitary Fibrous Tumor, Pleural / diagnosis*
  • Thoracotomy / methods
  • Tomography, X-Ray Computed

Supplementary concepts

  • Hereditary renal agenesis