The Impact of the Educational Intervention on Knowledge, Attitude, and Practice of Pharmacovigilance toward Adverse Drug Reactions Reporting among Health-care Professionals in a Tertiary Care Hospital in South India

Subramaniyan Ganesan; Selvarajan Sandhiya; Kishtapati Chenchu Reddy; D K Subrahmanyam; Chandrasekaran Adithan

doi:10.4103/0976-9668.210014

The Impact of the Educational Intervention on Knowledge, Attitude, and Practice of Pharmacovigilance toward Adverse Drug Reactions Reporting among Health-care Professionals in a Tertiary Care Hospital in South India

J Nat Sci Biol Med. 2017 Jul-Dec;8(2):203-209. doi: 10.4103/0976-9668.210014.

Authors

Subramaniyan Ganesan¹, Selvarajan Sandhiya², Kishtapati Chenchu Reddy³, D K Subrahmanyam⁴, Chandrasekaran Adithan⁵

Affiliations

¹ Department of Pharmacology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
² Department of Clinical Pharmacology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
³ Technical Associate, Pharmacovigilance Programme of India, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
⁴ Department of Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
⁵ Director, Central Inter Disciplinary Research Facility (CIDRF), Mahatma Gandhi Medical College and Research Institute, Puducherry, India.

Abstract

Background: Knowledge, attitude, practice (KAP)-based educational intervention is an important tool to reduce underreporting of adverse drug reactions (ADRs). Hence, this study aimed to assess the KAP of doctors and nurses working in medicine and allied departments of Jawaharlal Institute of Postgraduate Medical Education and Research on spontaneous reporting of ADRs, following an educational intervention. The study also compared the quantity of ADRs reported before and after 1 year of introducing the educational intervention.

Methodology: The study was a cross-sectional questionnaire-based study involving doctors and nurses working in a tertiary care hospital in South India. A predesigned structured questionnaire was prepared to suit our ADR monitoring center, validated and then distributed to doctors and nurses working in medicine and allied departments of the institute. The study participants were asked to fill KAP pretest questionnaire followed by interactive educational intervention and post-test questionnaire related to KAP after 1 year. The impact of educational intervention among doctors and nurses was evaluated by their response to the post-test questionnaire and the number of ADR reported after intervention. The appropriate statistical analysis was used through Graph Pad InStat version 3.0.

Results: A total of 235 health-care professionals were involved in the pre-KAP questionnaire, an educational intervention, and post-KAP questionnaire. Among them, doctors were 39%, and nurses were 61%. The overall response rate among doctors and nurses following educational intervention was statistically significant (P < 0.0001). Following the educational intervention, the quantity of ADR reported became double compared to pre-intervention.

Conclusion: The KAP of health-care professionals improved following educational interventional program on pharmacovigilance. Continued educational intervention may inculcate ADR reporting culture among health-care professionals.

Keywords: Adverse drug reaction; attitude; educational intervention; knowledge; pharmacovigilance; practice; questionnaire.