Neurological Complications of Gastrointestinal Disease

Semin Pediatr Neurol. 2017 Feb;24(1):43-53. doi: 10.1016/j.spen.2017.02.001. Epub 2017 Feb 4.

Abstract

There is a growing interest in the extraintestinal manifestations of common pediatric gastrointestinal diseases, such as inflammatory bowel disease and celiac disease. This article specifically focuses on the neurological symptoms that manifest because of these disorders and their treatments. Many neurological symptoms have been reported in association with these diseases, including neuropathy, myopathy, ataxia, headache, and seizures, among others. It is currently believed that these neurological symptoms are largely overlooked by practitioners and could be a red flag for earlier diagnosis. However, additional research, especially in the pediatric population, is warranted to further elaborate on the causality and pathophysiology of these neurological symptoms.

Publication types

  • Review

MeSH terms

  • Gastrointestinal Diseases / complications*
  • Gastrointestinal Diseases / epidemiology
  • Gastrointestinal Diseases / physiopathology
  • Humans
  • Nervous System Diseases / complications*
  • Nervous System Diseases / epidemiology
  • Nervous System Diseases / physiopathology