Circulating and skin-derived Sézary cells: clonal but with phenotypic plasticity

Marie Roelens; Marc Delord; Caroline Ram-Wolff; Anne Marie-Cardine; Antonio Alberdi; Guitta Maki; Laurence Homyrda; Armand Bensussan; Martine Bagot; Antoine Toubert; Hélène Moins-Teisserenc

doi:10.1182/blood-2017-03-772996

Circulating and skin-derived Sézary cells: clonal but with phenotypic plasticity

Blood. 2017 Sep 21;130(12):1468-1471. doi: 10.1182/blood-2017-03-772996. Epub 2017 Jul 31.

Authors

Marie Roelens^{1

2

3}, Marc Delord^{2

4}, Caroline Ram-Wolff^{2

5

6}, Anne Marie-Cardine^{2

5}, Antonio Alberdi^{2

7}, Guitta Maki³, Laurence Homyrda³, Armand Bensussan^{2

5}, Martine Bagot^{2

5

6}, Antoine Toubert^{1

2

3}, Hélène Moins-Teisserenc^{1

2

3}

Affiliations

¹ INSERM Unité Mixte de Recherche 1160, Institut Universitaire d'Hématologie, Paris, France.
² University of Paris Diderot, Sorbonne Paris Cité, Paris, France.
³ Assistance Publique-Hôpitaux de Paris, Laboratoire d'Immunologie-Histocompatibilité, Hôpital Saint Louis, Paris, France.
⁴ Biostatistics and Clinical Epidemiology, INSERM Unité Mixte de Recherche 1153, Paris, France.
⁵ INSERM Unité Mixte de Recherche 976, Unité de Formation et de Recherche de Médecine, Paris, France.
⁶ Assistance Publique-Hôpitaux de Paris, Service de Dermatologie, Hôpital Saint Louis, Paris, France; and.
⁷ Plateforme Technologique, Institut Universitaire d'Hématologie, Paris, France.

PMID: 28760889
DOI: 10.1182/blood-2017-03-772996

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Antigens, CD / analysis
Antigens, Neoplasm / analysis*
Biomarkers, Tumor / analysis
Cell Separation / methods
Clone Cells / chemistry
Clone Cells / pathology
Cytokines / analysis
Flow Cytometry / methods
Gene Rearrangement, beta-Chain T-Cell Antigen Receptor
Humans
Immunologic Memory
Immunophenotyping
Neoplastic Cells, Circulating*
Neoplastic Stem Cells / chemistry
Neoplastic Stem Cells / pathology
Receptors, Antigen, T-Cell, alpha-beta / genetics
Receptors, Cytokine / analysis
Receptors, KIR2DL2 / analysis*
Receptors, KIR3DL2 / analysis*
Sezary Syndrome / chemistry*
Sezary Syndrome / pathology
Skin / chemistry
Skin / pathology
Skin Neoplasms / chemistry*
Skin Neoplasms / pathology
T-Lymphocyte Subsets / chemistry*
T-Lymphocyte Subsets / pathology
Transcriptome

Substances

Antigens, CD
Antigens, Neoplasm
Biomarkers, Tumor
Cytokines
KIR2DL2 protein, human
KIR3DL2 protein, human
Receptors, Antigen, T-Cell, alpha-beta
Receptors, Cytokine
Receptors, KIR2DL2
Receptors, KIR3DL2