A Brief Review of OPT101 Sensor Application in Near-Infrared Spectroscopy Instrumentation for Intensive Care Unit Clinics

Ting Li; Fulin Zhong; Boan Pan; Zebin Li; Chong Huang; Zishan Deng

doi:10.3390/s17081701

A Brief Review of OPT101 Sensor Application in Near-Infrared Spectroscopy Instrumentation for Intensive Care Unit Clinics

Sensors (Basel). 2017 Jul 25;17(8):1701. doi: 10.3390/s17081701.

Authors

Ting Li^{1

2}, Fulin Zhong³, Boan Pan⁴, Zebin Li⁵, Chong Huang⁶, Zishan Deng⁷

Affiliations

¹ School of Microelectronics and Solid-state electronics, University of Electronic Science & Technology of China, Chengdu 610054, China. liting@uestc.edu.cn.
² Institute of Biomedical Engineering, Chinese Academy of Medical Science and Peking Union Medical College, Tianjin 300192, China. liting@uestc.edu.cn.
³ School of Microelectronics and Solid-state electronics, University of Electronic Science & Technology of China, Chengdu 610054, China. 201521031005@std.uestc.edu.cn.
⁴ School of Microelectronics and Solid-state electronics, University of Electronic Science & Technology of China, Chengdu 610054, China. 201621030444@std.uestc.edu.cn.
⁵ School of Microelectronics and Solid-state electronics, University of Electronic Science & Technology of China, Chengdu 610054, China. 201521031032@std.uestc.edu.cn.
⁶ Department of Biomedical Engineering, University of Kentucky, Lexington, Kentucky, KY 40506, USA. chong.huang@uky.edu.
⁷ School of Microelectronics and Solid-state electronics, University of Electronic Science & Technology of China, Chengdu 610054, China. 2013030102028@std.uestc.edu.cn.

Abstract

The optoelectronic sensor OPT101 have merits in advanced optoelectronic response characteristics at wavelength range for medical near-infrared spectroscopy and small-size chip design with build-in trans-impedance amplifier. Our lab is devoted to developing a series of portable near-infrared spectroscopy (NIRS) devices embedded with OPT101 for applications in intensive care unit clinics, based on NIRS principle. Here we review the characteristics and advantages of OPT101 relative to clinical NIRS instrumentation, and the most recent achievements, including early-diagnosis and therapeutic effect evaluation of thrombus, noninvasive monitoring of patients' shock severity, and fatigue evaluation. The future prospect on OPT101 improvements in noninvasive clinical applications is also discussed.

Keywords: fatigue evaluation; near-infrared spectroscopy; optoelectronic sensor; shock monitoring; thrombus diagnosis.

Publication types

Review

MeSH terms

Humans
Intensive Care Units
Spectroscopy, Near-Infrared*