Infectious complications related to external ventricular shunt. Incidence and risk factors

Rev Esp Quimioter. 2017 Oct;30(5):327-333. Epub 2017 Jul 25.
[Article in English, Spanish]

Abstract

Objective: Infectious complications related to external ventricular shunt (ICREVS) are a main problem in neurocritical intensive care units (ICU). The aim of the review is to assess the incidence of ICREVS and to analyse factors involved.

Methods: Retrospective analysis, adult polyvalent ICU in a third level reference hospital. Patients carrying external ventricular shunt (DVE) were included. Those patients with central nervous system infection diagnosed prior DVE placement were excluded.

Results: 87 patients were included with 106 DVE. Most common admittance diagnosis was subarachnoid haemorrhage (49.4%). 31 patients with 32 DVE developed an ICREVS. Infection rate is 19.5 per 1000 days of shunt for ICREVS and 14 per 1000 days for ventriculitis. 31.6% of the patients developed ICREVS and 25.3% ventriculitis. Patients who developed ICREVS presented higher shunt manipulations (2.0 ± 0.6 vs. 3.26 ± 1.02, p=0.02), shunt repositioning (0.1 ± 0.1 vs. 0.2 ± 0.1) and ICU and hospital stay (29.8 ± 4.9 vs 49.8 ± 5.2, p<0.01 y 67.4 ± 18.8 vs. 108.9 ± 30.2, p=0.02. Those DVE with ICREVS were placed for longer not only at infection diagnosis but also at removal (12.6 ± 2.1 vs. 18.3 ± 3.6 and 12.6 ± 2.1 vs. 30.4 ± 7.3 days, p<0.01). No difference in mortality was found.

Conclusions: One out of three patients with a DVE develops an infection. The risk factors are the number of manipulations, repositioning and the permanency days. Patients with ICREVS had a longer ICU and hospital average stay without an increase in mortality.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Catheter-Related Infections / epidemiology*
  • Catheter-Related Infections / mortality
  • Central Nervous System Bacterial Infections / epidemiology
  • Central Nervous System Bacterial Infections / mortality
  • Cerebral Ventriculitis / complications
  • Cerebral Ventriculitis / epidemiology
  • Cerebral Ventriculitis / therapy
  • Female
  • Hospital Mortality
  • Humans
  • Incidence
  • Intensive Care Units
  • Length of Stay
  • Male
  • Middle Aged
  • Retrospective Studies
  • Risk Factors
  • Spain / epidemiology
  • Subarachnoid Hemorrhage / complications
  • Subarachnoid Hemorrhage / epidemiology
  • Subarachnoid Hemorrhage / therapy
  • Ventriculoperitoneal Shunt / adverse effects*