Calcium phosphate-hybridized tendon grafts reduce femoral bone tunnel enlargement in anatomic single-bundle ACL reconstruction

Knee Surg Sports Traumatol Arthrosc. 2018 Feb;26(2):500-507. doi: 10.1007/s00167-017-4657-9. Epub 2017 Jul 26.

Abstract

Purpose: This study aimed to clarify the effect of calcium phosphate (CaP)-hybridized tendon grafting versus unhybridized tendon grafting on the morphological changes to the bone tunnels at the aperture 1 year after anatomic single-bundle anterior cruciate ligament (ACL) reconstruction.

Methods: Seventy-three patients were randomized to undergo the CaP (n = 37) or the conventional method (n = 36). All patients underwent computed tomography (CT) evaluation 1 week and 1 year post-operatively. The femoral and tibial tunnels at the aperture were evaluated on reconstructed 3D CT images. Changes in the cross-sectional area (CSA) and diameters of the femur and the tibia, and the translation rate of the tunnel walls and the morphological changes of both tunnels were assessed.

Results: There was a significant reduction in the increase in the CSA and the anterior-posterior and proximal-distal tunnel diameters on the femoral side in the CaP group as compared with the conventional group. On the femoral side, the translation rate of the posterior wall was significantly larger in the CaP group than in the conventional group, whereas the translation rate of the distal wall was significantly smaller in the CaP group than in the conventional group.

Conclusions: As compared with the conventional method, the CaP-hybridized tendon graft reduced bone tunnel enlargement on the femoral side 1 year after anatomic single-bundle ACL reconstruction due to an anterior shift of the posterior wall and reduced distal shift in the femoral bone tunnel. Clinically, the CaP-hybridized tendon grafts can prevent femoral bone tunnel enlargement in anatomic single-bundle ACL reconstruction.

Level of evidence: I.

Keywords: Anatomic single-bundle anterior cruciate ligament reconstruction; Bone tunnel enlargement; Calcium phosphate hybridization; Computed tomography; Tunnel morphology.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adolescent
  • Adult
  • Anatomy, Cross-Sectional
  • Anterior Cruciate Ligament Reconstruction / adverse effects
  • Anterior Cruciate Ligament Reconstruction / methods*
  • Bone Regeneration
  • Calcium Phosphates
  • Coated Materials, Biocompatible
  • Female
  • Femur / diagnostic imaging*
  • Femur / physiopathology
  • Femur / surgery
  • Hamstring Tendons / diagnostic imaging
  • Hamstring Tendons / transplantation
  • Humans
  • Imaging, Three-Dimensional
  • Male
  • Tendons / diagnostic imaging
  • Tendons / transplantation
  • Tibia / diagnostic imaging*
  • Tibia / physiopathology
  • Tibia / surgery
  • Tomography, X-Ray Computed
  • Wound Healing
  • Young Adult

Substances

  • Calcium Phosphates
  • Coated Materials, Biocompatible
  • calcium phosphate