Evaluation of complication rates and vertical bone gain after guided bone regeneration with non-resorbable membranes versus titanium meshes and resorbable membranes. A randomized clinical trial

Clin Implant Dent Relat Res. 2017 Oct;19(5):821-832. doi: 10.1111/cid.12520. Epub 2017 Jul 26.

Abstract

Background: The partial edentulous posterior mandible is often a challenge area that requires a bone reconstructive surgery for implants placement.

Purpose: This RCT was aimed to evaluate complications rate and vertical bone gain after Guided Bone Regeneration (GBR) with dense non-resorbable d-PTFE titanium-reinforced membranes (Group A) versus titanium meshes covered by cross-linked collagen membranes (Group B).

Material and methods: 40 partially edentulous patients with atrophic posterior mandible, were randomly divided into two study group: 20 patients were treated with one stage GBR by means of non-resorbable d-PTFE titanium-reinforced membranes (Group A); and 20 patients, by means of titanium mesh covered by cross-linked collagen membranes (Group B). All complications were recorded, distinguishing between "surgical" and "healing" and between "minor" or "major.". Primary implants stability and vertical bone gain were also evaluated.

Results: In the group A, surgical and healing complication rates were 5.0% and 15.0%, respectively. In the group B, surgical and healing complication rates were 15.8% and 21.1%, respectively. No significant differences between two study group were observed regarding complications rate implant stability and vertical bone gain.

Conclusions: Both GBR approaches for the restoration of atrophic posterior mandible achieved similar results regarding complications, vertical bone gain and implant stability.

Keywords: alveolar ridge reconstruction; atrophy; bone augmentation; bone defects; bone regeneration; edentulous mandible; guided bone regeneration.

Publication types

  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Absorbable Implants
  • Bone Regeneration*
  • Collagen*
  • Double-Blind Method
  • Female
  • Guided Tissue Regeneration, Periodontal*
  • Humans
  • Male
  • Membranes, Artificial*
  • Middle Aged
  • Pilot Projects
  • Polytetrafluoroethylene*
  • Postoperative Complications / epidemiology*
  • Surgical Mesh*
  • Titanium*

Substances

  • Membranes, Artificial
  • Polytetrafluoroethylene
  • Collagen
  • Titanium