B7-H4 enhances the differentiation of murine leukemia-initiating cells via the PTEN/AKT/RCOR2/RUNX1 pathways

Leukemia. 2017 Oct;31(10):2260-2264. doi: 10.1038/leu.2017.232. Epub 2017 Jul 24.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cell Differentiation / physiology*
  • Cell Line
  • Co-Repressor Proteins
  • Core Binding Factor Alpha 2 Subunit / metabolism*
  • Humans
  • Leukemia / metabolism*
  • Mice
  • Nerve Tissue Proteins / metabolism*
  • PTEN Phosphohydrolase / metabolism*
  • Proto-Oncogene Proteins c-akt / metabolism*
  • Repressor Proteins / metabolism*
  • Signal Transduction / physiology
  • V-Set Domain-Containing T-Cell Activation Inhibitor 1 / metabolism*

Substances

  • Co-Repressor Proteins
  • Core Binding Factor Alpha 2 Subunit
  • Nerve Tissue Proteins
  • Rcor2 protein, mouse
  • Repressor Proteins
  • Runx1 protein, mouse
  • V-Set Domain-Containing T-Cell Activation Inhibitor 1
  • Vtcn1 protein, mouse
  • Proto-Oncogene Proteins c-akt
  • PTEN Phosphohydrolase
  • Pten protein, mouse