[Remifentanil Up2date - Part 1]

Anasthesiol Intensivmed Notfallmed Schmerzther. 2017 Jul;52(7-08):543-553. doi: 10.1055/s-0042-122041. Epub 2017 Jul 25.
[Article in German]

Abstract

Remifentanil is a short-acting opioid of high analgetic potency and superior controllability. It is widely used in day-case surgery, procedural sedation, for reduction of recovery-times and obstetrics and whenever excellent controllability of opioid effects is needed. Especially in combination with Propofol it is used for target-controlled infusion (TCI). The first part of the article provides readers with information about historical aspects, pharmacological characteristics, effects and side effects of remifentanil.

Remifentanil ist ein kurzwirksames, potentes Opioid mit guter Steuerbarkeit – und vor allem in der ambulanten Anästhesiologie nahezu unverzichtbar. Umso härter trifft uns die seit 2016 eingeschränkte Verfügbarkeit und Kontingentierung. Dieser Beitrag liefert einen Überblick über die Substanz, ihre Geschichte und pharmakologischen Eigenschaften.

Publication types

  • Review

MeSH terms

  • Adult
  • Analgesia, Patient-Controlled
  • Analgesics, Opioid / adverse effects
  • Analgesics, Opioid / pharmacology
  • Analgesics, Opioid / therapeutic use*
  • Anesthesia
  • Anesthetics, Intravenous
  • Drug Interactions
  • Female
  • Humans
  • Infusions, Intravenous
  • Pain, Postoperative / drug therapy*
  • Piperidines / adverse effects
  • Piperidines / pharmacology
  • Piperidines / therapeutic use*
  • Pregnancy
  • Remifentanil

Substances

  • Analgesics, Opioid
  • Anesthetics, Intravenous
  • Piperidines
  • Remifentanil