Clostridium perfringens and C. difficile in parvovirus-positive dogs

Anaerobe. 2017 Dec:48:66-69. doi: 10.1016/j.anaerobe.2017.07.001. Epub 2017 Jul 19.

Abstract

The aim of this study was to investigate Clostridium difficile and Clostridium perfringens in 82 diarrheic dogs positive for canine parvovirus type 2 (CPV). Enterotoxigenic C. perfringens type A was isolated from three (3.6%) dogs. One (1.2%) strain was also positive for NetE- and NetF-encoding genes, which are commonly associated with diarrhea in dogs. Toxigenic C. difficile was isolated from one animal (1.2%), which was also positive for A/B toxins. The present study identified C. difficile and C. perfringens infection in CPV-positive dogs. Further studies are necessary to clarify if clostridial infections may predispose or potentiate CPV-infection in dogs or vice versa.

Keywords: CPV-2b; Canine; Diarrhea; Hemorrhagic enteritis; Parvovirus.

MeSH terms

  • Animals
  • Bacterial Proteins / metabolism
  • Bacterial Toxins / metabolism
  • Clostridioides difficile / isolation & purification*
  • Clostridium Infections / veterinary*
  • Clostridium perfringens / isolation & purification*
  • Coinfection / microbiology*
  • Coinfection / virology*
  • Diarrhea / microbiology
  • Diarrhea / veterinary
  • Dog Diseases / microbiology
  • Dog Diseases / virology
  • Dogs
  • Enterotoxins / metabolism
  • Parvoviridae Infections / veterinary*
  • Parvovirus, Canine / genetics
  • Parvovirus, Canine / isolation & purification*

Substances

  • Bacterial Proteins
  • Bacterial Toxins
  • Enterotoxins
  • tcdA protein, Clostridium difficile
  • toxB protein, Clostridium difficile