Multicenter study of pars plana vitrectomy for optic disc pit maculopathy: MACPIT study

Eye (Lond). 2017 Sep;31(9):1266-1273. doi: 10.1038/eye.2017.142. Epub 2017 Jul 21.

Abstract

PurposeTo evaluate surgical intervention with pars plana vitrectomy (PPV) for correction of optic disc pit maculopathy (ODP-M).Patients and methodsRetrospective chart review from 13 centres of 51 eyes of 50 patients with ODP-M who underwent PPV between 2002-2014. Anatomic and final best-corrected visual acuity (BCVA) outcomes were evaluated for all cases with different adjuvant techniques.ResultsThere were 23 males and 27 females with median age 25.5 (6-68) years. Preoperative median foveal thickness was 694.5 (331-1384) μm and improved to 252.5 (153-1405) μm. Median BCVA improved from 20/200 (20/20000 to 20/40) to 20/40 (20/2000 to 20/20) with 20/40 or better in 31 eyes. Complete retinal reattachment was achieved in 44 eyes (86.3%) at 7.1 (5.9) months. The good surgical outcomes were achieved in different adjuvant groups. Median follow-up was 24 (6 to 120) months.ConclusionsThese results confirm the long-term effectiveness of PPV for ODP-M. Prospective studies are needed to determine the effectiveness of any adjuvant technique in improving the success of PPV for ODP-M.

Publication types

  • Multicenter Study

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Child
  • Endotamponade
  • Eye Abnormalities / diagnosis
  • Eye Abnormalities / physiopathology
  • Eye Abnormalities / surgery*
  • Female
  • Fluorocarbons / administration & dosage
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Optic Disk / abnormalities*
  • Retinal Diseases / diagnosis
  • Retinal Diseases / physiopathology
  • Retinal Diseases / surgery*
  • Retrospective Studies
  • Sulfur Hexafluoride / administration & dosage
  • Tomography, Optical Coherence
  • Visual Acuity / physiology
  • Vitrectomy / methods*

Substances

  • Fluorocarbons
  • perfluoroethane
  • perflutren
  • Sulfur Hexafluoride