MeClas: An online tool for hazard identification and classification of complex inorganic metal-containing materials

Regul Toxicol Pharmacol. 2017 Oct:89:232-239. doi: 10.1016/j.yrtph.2017.07.015. Epub 2017 Jul 17.

Abstract

MeClas is a web-based tool to generate (eco)toxicity hazard categories and corresponding classification & labelling information of inorganic metal-containing complex materials such as ores, concentrates, intermediates or alloys for which the manual application of the GHS/CLP rules is very complex and requires a high level of consistency. The tool comprises several tiers, aimed at the progressive refinement of classification through recognition of specific mineral content, speciation/mineralogy up to bio-availability corrections. Where relevant in a regional jurisdiction (EU and US), mandatory classification references are used complementary to high quality (eco)toxicity reference values (ERV/TRV) and self-classifications. MeClas addresses the GHS human health and environmental hazard endpoints, is based on an unambiguous algorithm defined under GHS/CLP, has a well defined domain of applicability and robust predictability. MeClas allows a consistent approach across companies in line with GHS ruling (and regional implementations), considering the metal specificities and related classification GHS/CLP Guidance, and the most up to date (eco)-toxicological hazard information on self-classifications and ERV/TRV.

Keywords: Alloys; Bioavailability; Classification; GHS and CLP; Labelling; Metals; OSHA; Ores and concentrates; UVCB.

MeSH terms

  • Alloys / chemistry
  • Humans
  • Inorganic Chemicals / analysis*
  • Metals / analysis*
  • Online Systems*

Substances

  • Alloys
  • Inorganic Chemicals
  • Metals