Celastrol specifically inhibits the activation of NLRP3 inflammasome

Sci China Life Sci. 2018 Mar;61(3):355-357. doi: 10.1007/s11427-017-9048-8. Epub 2017 Jul 18.

Xuesong Sang^{1

2}, Yihui Chen¹, Wei Chen¹, Jing Xie^{3

4}, Guangxun Meng¹, Jin Zhong¹, Taisheng Li^{5

6}, Ailing Lu⁷

¹ CAS Key Laboratory of Molecular Virology & Immunology, Institute Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, 200031, China.
² School of Life Sciences, Shanghai University, Shanghai, 200444, China.
³ Department of Infectious Diseases, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, 100730, China.
⁴ Clinical Immunology Center, Chinese Academy of Medical Sciences, Beijing, 100730, China.
⁵ Department of Infectious Diseases, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, 100730, China. litsh@263.net.
⁶ Clinical Immunology Center, Chinese Academy of Medical Sciences, Beijing, 100730, China. litsh@263.net.
⁷ CAS Key Laboratory of Molecular Virology & Immunology, Institute Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, 200031, China. allu@ips.ac.cn.

No abstract available

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