Abstract
A review is presented of functional studies performed with the expanded T cells in Sézary syndrome, T-cell chronic lymphocytic leukemia (T-CLL), T-prolymphocytic leukemia (T-PLL), adult T-cell leukemia lymphoma (ATLL), T-cell acute lymphoblastic leukemia (T-ALL) and T gamma lymphocytosis. The immunological and clinical relevance of immunological studies of functional properties of T-cell expansions is discussed.
MeSH terms
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Deltaretrovirus Infections / immunology*
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Humans
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Immunoglobulins / biosynthesis
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Interleukin-2 / biosynthesis
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Killer Cells, Natural / immunology
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Lymphocytosis / immunology*
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Receptors, Antigen, T-Cell / genetics
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Receptors, Fc / analysis
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Recombination, Genetic
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Sezary Syndrome / immunology
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T-Lymphocytes / immunology*
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T-Lymphocytes, Helper-Inducer / immunology
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T-Lymphocytes, Regulatory / immunology
Substances
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Immunoglobulins
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Interleukin-2
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Receptors, Antigen, T-Cell
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Receptors, Fc