Thiamine deficiency in metronidazole-induced encephalopathy: A metabolic correlation?

Dosuke Iwadate; Kenichiro Sato; Mami Kanzaki; Chinatsu Komiyama; Chizuru Watanabe; Tomoaki Eguchi; Yoshikazu Uesaka

doi:10.1016/j.jns.2017.06.042

Thiamine deficiency in metronidazole-induced encephalopathy: A metabolic correlation?

J Neurol Sci. 2017 Aug 15:379:324-326. doi: 10.1016/j.jns.2017.06.042. Epub 2017 Jun 27.

Authors

Dosuke Iwadate¹, Kenichiro Sato², Mami Kanzaki¹, Chinatsu Komiyama¹, Chizuru Watanabe³, Tomoaki Eguchi⁴, Yoshikazu Uesaka¹

Affiliations

¹ Department of Neurology, Toranomon Hospital, Okinaka Memorial Institute for Medical Research, Tokyo, Japan.
² Department of Neurology, Toranomon Hospital, Okinaka Memorial Institute for Medical Research, Tokyo, Japan. Electronic address: kenisatou-tky@umin.ac.jp.
³ Department of Endocrinology and Metabolism, Toranomon Hospital, Japan.
⁴ Department of Plastic Surgery, Toranomon Hospital, Japan.

PMID: 28716273
DOI: 10.1016/j.jns.2017.06.042

No abstract available

Keywords: Metronidazole; Metronidazole neurotoxicity; Metronidazole-induced encephalopathy; Thiamine; Thiamine deficiency; Wernicke encephalopathy.

Publication types

Case Reports
Letter

MeSH terms

Aged
Brain Diseases / chemically induced*
Brain Diseases / complications*
Brain Diseases / diagnostic imaging
Brain Diseases / metabolism
Humans
Magnetic Resonance Imaging
Male
Metronidazole / adverse effects*
Neuroimaging
Thiamine Deficiency / complications*
Thiamine Deficiency / diagnostic imaging
Thiamine Deficiency / metabolism*

Substances

Metronidazole