Abstract
The presence of a patent foramen ovale (PFO) has been found to be associated with an increased risk of cryptogenic stroke in many case-control studies. This paper reviews the current understanding of the pathophysiology and diagnosis of PFO, and therapeutic options of patients with PFO and cryptogenic stroke.
Keywords:
Antithrombotic treatment; Cryptogenic stroke; Echocardiography; Patent foramen ovale.
Copyright © 2017 Elsevier Inc. All rights reserved.
MeSH terms
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Echocardiography, Doppler, Color
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Echocardiography, Three-Dimensional
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Embolism, Paradoxical / complications*
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Embolism, Paradoxical / diagnostic imaging
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Embolism, Paradoxical / physiopathology
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Embolism, Paradoxical / therapy
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Foramen Ovale, Patent / complications*
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Foramen Ovale, Patent / diagnostic imaging
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Foramen Ovale, Patent / physiopathology
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Foramen Ovale, Patent / therapy
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Humans
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Predictive Value of Tests
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Prognosis
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Recurrence
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Risk Assessment
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Risk Factors
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Stroke / diagnostic imaging
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Stroke / etiology*
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Stroke / physiopathology
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Stroke / prevention & control