Complete genome sequence of the Bifidobacterium animalis subspecies lactis BL3, preventive probiotics for acute colitis and colon cancer

J Kang; W-H Chung; T-J Lim; S Lim; Y-D Nam

doi:10.1016/j.nmni.2017.05.012

Complete genome sequence of the Bifidobacterium animalis subspecies lactis BL3, preventive probiotics for acute colitis and colon cancer

New Microbes New Infect. 2017 May 27:19:34-37. doi: 10.1016/j.nmni.2017.05.012. eCollection 2017 Sep.

Authors

J Kang^{1

2}, W-H Chung¹, T-J Lim³, S Lim³, Y-D Nam^{1

2}

Affiliations

¹ Research Group of Gut Microbiome, Korea Food Research Institute, Sungnam, Republic of Korea.
² Department of Food Biotechnology, Korea University of Science and Technology, Daejeon, Republic of Korea.
³ Research and Development Center, Cell Biotech Co. Ltd., Gimpo, Republic of Korea.

Abstract

We report the genome sequence of Bifidobacterium animalis subspecies lactis BL3, which has preventive properties on acute colitis and colon cancer. The genome of BL3, which was isolated from Korean faeces, consisted of a 1 944 323 bp size single chromosome, and its G+C content was 60.5%. Genome comparison against the closest Bifidobacterium animalis strain revealed that BL3 had particularly different regions of four areas encoding flavin-nucleotide-binding protein, transposase, multidrug ABC transporter and ATP binding protein.

Keywords: Bifidobacterium; IBD; PacBio; genome sequence; probiotics.