Extracellular matrix stiffness affects contractility in adult rat cardiomyocytes: implications for dynamic nitric oxide signalling and calcium handling

J Physiol. 2017 Sep 1;595(17):5759-5760. doi: 10.1113/JP274787. Epub 2017 Jul 30.

Authors

Neal Ingraham Callaghan^{1

2}, Xavier Alexander Lee^{2

3}

Affiliations

¹ Institute of Biomaterials and Biomedical Engineering, Faculty of Applied Science and Engineering, University of Toronto, Toronto, ON, Canada.
² Translational Biology and Engineering Program, Ted Rogers Centre for Heart Research, Toronto, ON, Canada.
³ Department of Physiology, Faculty of Medicine, University of Toronto, Toronto, ON, Canada.

No abstract available

Keywords: cardiomyocyte; excitation-contraction coupling; muscle stiffness; nitric oxide.

Publication types

Research Support, Non-U.S. Gov't
Comment

MeSH terms

Animals
Calcium*
Extracellular Matrix
Myocardial Contraction
Myocytes, Cardiac*
Nitric Oxide
Rats

Substances

Nitric Oxide
Calcium