The Association Between Particulate Matter Air Pollution and Respiratory Health in Elderly With Type 2 Diabetes Mellitus

J Occup Environ Med. 2017 Sep;59(9):830-834. doi: 10.1097/JOM.0000000000001077.

Abstract

Objective: We investigated the association between respiratory health and particulate matter (PM) air pollution in elderly type 2 diabetes mellitus (T2DM) pre-, during, and post-the Chinese Lunar New Year (CLNY) holiday in Shanghai, China.

Methods: We conducted repeated measurements of lung function and inflammation biomarker in a cohort consisted of 60 participants with T2DM.

Results: Decreased PM2.5 exposure had an effect on respiratory health by increasing in forced expiratory flow in 1 second (FEV1) and forced vital capacity (FVC). Positive associations between PM exposure and exhaled nitric oxide (eNO) were observed.

Conclusions: Our observations indicated that PM air pollution exposure would exert adverse effect on respiratory health in elderly T2DM population.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Air Pollution
  • Breath Tests
  • China
  • Diabetes Mellitus, Type 2 / physiopathology*
  • Environmental Exposure / adverse effects*
  • Female
  • Forced Expiratory Volume
  • Humans
  • Male
  • Middle Aged
  • Nitric Oxide / analysis*
  • Particulate Matter / toxicity*
  • Vital Capacity

Substances

  • Particulate Matter
  • Nitric Oxide