To evaluate the effect of surgery on 47 patients with moyamoya disease by retrospective analysis. Methods: A total of 47 patients with moyamoya disease were enrolled from August, 2010 to According to the improved treatment in August, 2013, all cases were divided into two groups: a pre-improved group and a post-improved group. According to different surgical methods, they were divided into two subgroups: an indirect revascularization subgroup and a combined revascularization subgroup. Results: The cerebral ischemia in 77.4% of patients was relieved after the surgery. There was significant difference in outcomes of patients between the pre-improved group and the post-improved group (P<0.05), while there was no significant difference between the pre-improved indirect revascularization subgroup and the pre-improved combined revascularization subgroup. There was also no significant difference between the post-improved indirect revascularization subgroup and the post-improved combined revascularization subgroups (P>0.05). Conclusion: Surgical treatment can improve the outcomes of patients with moyamoya disease, but there is no significant difference in surgical effects between indirect and combined revascularization.
目的：回顾性分析经手术治疗的烟雾病患者的临床资料，评价手术疗效。方法：2010年8月至2015年8月共47例53侧烟雾病患者进行了间接或联合颅内外血管重建手术治疗，因2013年8月后改进了手术方法，故依此时间点将患者分为手术方法改进前组和改进后组，再根据术式的不同，进一步将患者分为间接手术亚组和联合手术亚组，并比较其疗效。结果：77.4%的患者通过颅内外血管重建手术可以改善脑缺血，手术方法改进前组和改进后组的手术疗效和术后并发脑卒中率差异有统计学意义(P<0.05)，而2组内采用不同术式的手术疗效差异无统计学意义(P>0.05)。结论：通过缩短烟雾病的手术时间和延期手术可以明显提高手术疗效和降低术后脑卒中发生率；而采用不同的术式疗效并无明显差异。.