Metabolite profiling in early clinical drug development: current status and future prospects

Expert Opin Drug Metab Toxicol. 2017 Aug;13(8):803-806. doi: 10.1080/17425255.2017.1351944. Epub 2017 Jul 13.

Authors

Mike Ufer¹, Pierre-Eric Juif¹, Marie-Laure Boof¹, Clemens Muehlan¹, Jasper Dingemanse¹

Affiliation

¹ a Department of Clinical Pharmacology , Idorsia Pharmaceuticals Ltd , Allschwil , Switzerland.

PMID: 28689432
DOI: 10.1080/17425255.2017.1351944

No abstract available

Keywords: Metabolite profiling; drug development; human ADME; metabolomics; micro-dose; micro-tracer.

Publication types

Editorial

MeSH terms

Animals
Drug Design*
Drug Interactions
Humans
Metabolomics / methods*
Pharmaceutical Preparations / metabolism*
Pharmacokinetics*

Substances

Pharmaceutical Preparations