Invasive Fungal Infections in the Intensive Care Unit

Luis Ostrosky-Zeichner; Mohanad Al-Obaidi

doi:10.1016/j.idc.2017.05.005

Invasive Fungal Infections in the Intensive Care Unit

Infect Dis Clin North Am. 2017 Sep;31(3):475-487. doi: 10.1016/j.idc.2017.05.005. Epub 2017 Jul 5.

Authors

Luis Ostrosky-Zeichner¹, Mohanad Al-Obaidi²

Affiliations

¹ Division of Infectious Diseases, Department of Internal Medicine, University of Texas Health Science Center at Houston, 6431 Fannin MSB 2.112, Houston, TX 77030, USA.
² Division of Infectious Diseases, Department of Internal Medicine, University of Texas Health Science Center at Houston, 6431 Fannin MSB 2.112, Houston, TX 77030, USA. Electronic address: mohanad.m.alobaidi@uth.tmc.edu.

PMID: 28687215
DOI: 10.1016/j.idc.2017.05.005

Abstract

Patients in the intensive care unit are exposed to multiple stressors that predispose them to invasive fungal infections (IFIs), which carry high morbidity and mortality. Getting acquainted with the diagnostic methods and therapies is imperative for patient safety and for providing high-quality health care. This article focuses on the most frequent IFIs: invasive candidiasis and invasive aspergillosis.

Keywords: Antifungal; Aspergillosis; Candidiasis; Fungal infection; ICU.

Publication types

Review

MeSH terms

Antifungal Agents / administration & dosage
Antifungal Agents / therapeutic use*
Candidiasis, Invasive* / blood
Candidiasis, Invasive* / diagnosis
Candidiasis, Invasive* / drug therapy
Candidiasis, Invasive* / microbiology
Disease Management
Humans
Intensive Care Units*
Invasive Fungal Infections* / diagnosis
Invasive Fungal Infections* / drug therapy
Invasive Pulmonary Aspergillosis* / diagnosis
Invasive Pulmonary Aspergillosis* / drug therapy
Molecular Diagnostic Techniques
Risk Factors

Substances

Antifungal Agents