WITHDRAWN: Curcumin shifts RAS-induced pro-proliferative MEK/ERK-signaling toward pro-apoptotic p38MAPK/JNK1-signaling, triggering p53 activation and apoptosis

J Biol Chem. 2017 Jul 6:jbc.M117.784868. doi: 10.1074/jbc.M117.784868. Online ahead of print.

Abstract

This article has been withdrawn by the authors. A mistake was made during the preparation of Fig 1C, NKE panel. The Western blot data shown for p-ERK1/2 and actin are not from this set, but rather a similar set of data from a different experiment. The authors apologize to the readers.

Keywords: RAF/MEK/ERK; Ras protein; apoptosis; c-Jun N-terminal kinase (JNK); colorectal cancer; p38MAPK; p53.