Phytochemical Studies on Two Australian Anigozanthos Plant Species

J Nat Prod. 2017 Jul 28;80(7):2141-2145. doi: 10.1021/acs.jnatprod.7b00063. Epub 2017 Jul 6.

Abstract

Phytochemical studies of two Australian Anigozanthos (kangaroo paw) species, A. rufus and A. pulcherrimus, resulted in the identification of 13 secondary metabolites. 2-Amino-6-O-p-coumarylheptanedioic acid (3) and chalcone-5'-O-(4-O-p-coumaryl)-O-β-d-glucopyranoside (12) are reported as new compounds and are accompanied by nine flavonoids (2, 5-11, 13) and two anthocyanins (1, 4). Compounds 1 and 4 were isolated as red solids from A. rufus and are likely responsible for the coloration of the flowers. Compounds 1, 3, and 6 showed weak antimicrobial activities against Acinetobacter baumannii ATCC 19606 at concentrations of 52.4, 94.9, and 53.9 μM, respectively.

MeSH terms

  • Acinetobacter baumannii / drug effects
  • Anthocyanins / chemistry
  • Anthocyanins / pharmacology
  • Anti-Bacterial Agents / chemistry
  • Anti-Bacterial Agents / isolation & purification*
  • Anti-Bacterial Agents / pharmacology
  • Australia
  • Chromatography, High Pressure Liquid
  • Dose-Response Relationship, Drug
  • Flavonoids / chemistry
  • Flavonoids / isolation & purification*
  • Flavonoids / pharmacology
  • Flowers / chemistry
  • Glycosides / chemistry
  • Glycosides / isolation & purification
  • Glycosides / pharmacology
  • Magnoliopsida / chemistry*
  • Microbial Sensitivity Tests
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Phytochemicals / chemistry
  • Phytochemicals / isolation & purification

Substances

  • Anthocyanins
  • Anti-Bacterial Agents
  • Flavonoids
  • Glycosides
  • Phytochemicals