Abstract
Phytochemical studies of two Australian Anigozanthos (kangaroo paw) species, A. rufus and A. pulcherrimus, resulted in the identification of 13 secondary metabolites. 2-Amino-6-O-p-coumarylheptanedioic acid (3) and chalcone-5'-O-(4-O-p-coumaryl)-O-β-d-glucopyranoside (12) are reported as new compounds and are accompanied by nine flavonoids (2, 5-11, 13) and two anthocyanins (1, 4). Compounds 1 and 4 were isolated as red solids from A. rufus and are likely responsible for the coloration of the flowers. Compounds 1, 3, and 6 showed weak antimicrobial activities against Acinetobacter baumannii ATCC 19606 at concentrations of 52.4, 94.9, and 53.9 μM, respectively.
MeSH terms
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Acinetobacter baumannii / drug effects
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Anthocyanins / chemistry
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Anthocyanins / pharmacology
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Anti-Bacterial Agents / chemistry
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Anti-Bacterial Agents / isolation & purification*
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Anti-Bacterial Agents / pharmacology
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Australia
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Chromatography, High Pressure Liquid
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Dose-Response Relationship, Drug
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Flavonoids / chemistry
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Flavonoids / isolation & purification*
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Flavonoids / pharmacology
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Flowers / chemistry
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Glycosides / chemistry
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Glycosides / isolation & purification
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Glycosides / pharmacology
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Magnoliopsida / chemistry*
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Microbial Sensitivity Tests
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Molecular Structure
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Nuclear Magnetic Resonance, Biomolecular
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Phytochemicals / chemistry
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Phytochemicals / isolation & purification
Substances
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Anthocyanins
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Anti-Bacterial Agents
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Flavonoids
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Glycosides
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Phytochemicals