Seroreactivity to Anisakis spp. in the perinatal period

Obstet Med. 2017 Jun;10(2):96-98. doi: 10.1177/1753495X16689443. Epub 2017 Feb 1.

Abstract

Background: This study had sought to assess the seroreactivity to the fish nematode Anisakis spp. in a puerperal population, as well as to ascertain whether a correlation exists between maternal and cord blood levels.

Methods: Blood samples were obtained from puerperal women and cord blood to measure specific anti-Anisakis antigen IgG and IgE by ELISA. Non-parametric tests were used to compare two or more independent and related samples.

Results: Of the 99 maternal serum samples assessed, 21 were positive on ELISA (21.2%). There were no significant differences in the mean ranks of IgG optical density levels between women who ate fish and those who did not (p = 0.456), those who ate raw fish and those who did not (p = 0.479), or between those who had allergic complaints and those who did not (p = 0.431).

Conclusion: Transplacental passage of antibodies occurred, leading to moderate correlation between maternal and cord blood serum levels.

Keywords: Parasitology; immunology; maternal–fetal medicine; nutrition.