Ac2-26 peptide and serine protease of Bothrops atrox similarly induces angiogenesis without triggering local and systemic inflammation in a murine model of dorsal skinfold chamber

Toxicon. 2017 Oct:137:7-14. doi: 10.1016/j.toxicon.2017.06.009. Epub 2017 Jul 1.
No abstract available

Keywords: Angiogenesis; Annexin A1; Cytokines; Inflammatory cells; Neovascularization; Skin fragments.

MeSH terms

  • Animals
  • Annexin A1 / pharmacology*
  • Bothrops*
  • Crotalid Venoms / pharmacology*
  • Cytokines / blood
  • Disease Models, Animal
  • Female
  • Inflammation / immunology
  • Macrophages / immunology
  • Mast Cells / immunology
  • Mice
  • Mice, Inbred BALB C
  • Neovascularization, Physiologic / drug effects*
  • Peptides / pharmacology*
  • Serine Proteases / pharmacology*
  • Skin / blood supply*

Substances

  • Annexin A1
  • Crotalid Venoms
  • Cytokines
  • Peptides
  • annexin A1 peptide (2-26)
  • Serine Proteases