Complete genome sequence of bacteriocin-producing Lactobacillus plantarum KLDS1.0391, a probiotic strain with gastrointestinal tract resistance and adhesion to the intestinal epithelial cells

Genomics. 2017 Oct;109(5-6):432-437. doi: 10.1016/j.ygeno.2017.06.008. Epub 2017 Jul 1.

Abstract

Lactobacillus plantarum KLDS1.0391 is a probiotic strain isolated from the traditional fermented dairy products and identified to produce bacteriocin against Gram-positive and Gram-negative bacteria. Previous studies showed that the strain has a high resistance to gastrointestinal stress and has a high adhesion ability to the intestinal epithelial cells (Caco-2). We reported the entire genome sequence of this strain, which contains a circular 2,886,607-bp chromosome and three circular plasmids. Genes, which are related to the biosynthesis of bacteriocins, the stress resistance to gastrointestinal tract environment and adhesive performance, were identified. Whole genome sequence of Lactobacillus plantarum KLDS1.0391 will be helpful for its applications in food industry.

Keywords: Adhesion; Bacteriocin; Gastrointestinal tract resistance; Genome; Lactobacillus plantarum KLDS1.0391.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacterial Adhesion
  • Bacterial Proteins / genetics
  • Bacteriocins / biosynthesis*
  • Bacteriocins / genetics
  • Caco-2 Cells
  • Gastrointestinal Tract / microbiology
  • Genome Size
  • Genome, Bacterial*
  • Humans
  • Lactobacillus plantarum / genetics
  • Lactobacillus plantarum / physiology*
  • Multigene Family
  • Probiotics
  • Sequence Analysis, DNA / methods*
  • Stress, Physiological

Substances

  • Bacterial Proteins
  • Bacteriocins