Antitumour bioactive peptides isolated from marine organisms

Haibo Xing; Mengting Tong; Nanyu Jiang; Xiaomin Zhang; Hong Hu; Hongming Pan; Da Li

doi:10.1111/1440-1681.12808

Antitumour bioactive peptides isolated from marine organisms

Clin Exp Pharmacol Physiol. 2017 Nov;44(11):1077-1082. doi: 10.1111/1440-1681.12808.

Authors

Haibo Xing¹, Mengting Tong², Nanyu Jiang², Xiaomin Zhang², Hong Hu², Hongming Pan², Da Li²

Affiliations

¹ Department of ICU, Xiasha Campus, Sir Run Run Shaw Hospital Affiliated to Zhejiang University, School of Medicine, Hangzhou, China.
² Department of Medical Oncology, Sir Run Run Shaw Hospital Affiliated to Zhejiang University, School of Medicine, Hangzhou, China.

PMID: 28675498
DOI: 10.1111/1440-1681.12808

Abstract

Marine organisms are an important source of antitumour active substances. Thus, pharmaceutical research in recent years has focused on exploring new antitumour drugs derived from marine organisms, and, many peptide drugs with strong antitumour activities have been successfully extracted. Based on different mechanisms, this paper reviews the research on several typical antitumour bioactive peptides in marine drugs and the latest progress therein. Additionally, the development prospects for these antitumour bioactive peptide-based drugs are discussed so as to provide a reference for future research in this field.

Keywords: antitumour; bioactive peptides; marine organisms.

Publication types

Review

MeSH terms

Animals
Antineoplastic Agents / chemistry
Antineoplastic Agents / pharmacology*
Aquatic Organisms / chemistry*
Drug Discovery
Humans
Peptides / chemistry
Peptides / pharmacology*
Protein Biosynthesis / drug effects

Substances

Antineoplastic Agents
Peptides