The relationship between protein quantity, BMD and fractures in older adults

Ir J Med Sci. 2018 Feb;187(1):111-121. doi: 10.1007/s11845-017-1642-8. Epub 2017 Jul 3.

Abstract

Background: Previously, no large-scale literature reviews have focussed on the relationship between dietary protein and its impact on bone mineral density (BMD) and fracture risk-as measures of bone health-in older adults and its potential impact as a primary prevention tool.

Aims: The aim of this study was to assess the impact of varying dietary protein levels on bone health.

Methods: A literature review of trials concerning older adults' (>50 years of age) and animals' varying protein intake in the diet and its effect on BMD (human and animal) and fracture risk (human only) was carried out. Additionally, a review of dietary assessment tools used in these studies was also analysed.

Results: Ten out of fourteen trials assessing BMD and dietary protein quantity in humans and 3/4 in animal trials found a positive relationship between these two parameters. Four out of seven trials investigating the relationship between dietary protein quantity and fracture risk displayed a positive, protective effect of dietary protein levels on fracture risk. Sixty-two percent of studies used the Food-Frequency Questionnaire assessment method.

Discussion: Increased protein intake in the diet is beneficial to bone health and reduces morbidity and mortality. The importance of using dietary protein, along with calcium and vitamin D, as a primary preventative strategy should be stressed, given the health and cost benefits that this would deliver, with a possible need for a higher level of protein in the diet of an elderly person than what is currently recommended.

Keywords: BMD; Elderly; Fracture; Nutrition; Protein.

Publication types

  • Review

MeSH terms

  • Bone Density / physiology*
  • Female
  • Fractures, Bone / etiology*
  • Humans
  • Male
  • Middle Aged
  • Proteins / chemistry*

Substances

  • Proteins