SLNB in cutaneous SCC: A review of the current state of literature and the direction for the future

J Surg Oncol. 2017 Sep;116(3):344-350. doi: 10.1002/jso.24675. Epub 2017 Jul 3.

Abstract

The concept of the sentinel lymph node biopsy (SLNB) has been universally accepted for melanoma, however, remains controversial for squamous cell carcinoma (SCC). We performed a quantitative review on 260 cases of SCC that had a SLNB. The positivity rate was found to be 14.6%. Literature was qualitatively reviewed to determine whether a positive SLNB has any bearing on prognosis in SCC cases, finding a significant relationship between poor prognosis and a positive SLN (P = 0.0082).

Keywords: SCC; SLNB; high-risk.

Publication types

  • Review

MeSH terms

  • Carcinoma, Squamous Cell / pathology*
  • Humans
  • Predictive Value of Tests
  • Sentinel Lymph Node Biopsy*
  • Skin Neoplasms / pathology*