Novel sequence variants of viral hexon and fibre genes in two dogs with canine adenovirus type 1-associated disease

Vet J. 2017 May:223:73-75. doi: 10.1016/j.tvjl.2017.05.011. Epub 2017 May 31.

Abstract

There is little information on sequence variation of canine adenovirus type 1 (CAdV-1), the aetiological agent of infectious canine hepatitis (ICH). This study reports hexon and fibre gene sequence variants of CAdV-1 in a dog with systemic ICH and a dog with the ocular form of the disease ('blue eye') in Northern Italy in 2013. One of the sequence variants matched a CAdV-1 fox sequence previously detected in Italy.

Keywords: Anterior uveitis; Canine adenovirus type 1; Infectious canine hepatitis; Sequence variants.

Publication types

  • Case Reports

MeSH terms

  • Adenoviridae Infections / veterinary*
  • Adenoviridae Infections / virology
  • Adenoviruses, Canine / genetics*
  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Capsid Proteins / chemistry
  • Capsid Proteins / genetics*
  • Dogs
  • Eye Diseases / veterinary*
  • Eye Diseases / virology
  • Genetic Variation / genetics*
  • Hepatitis, Infectious Canine / virology*
  • Italy
  • Male

Substances

  • Capsid Proteins
  • hexon capsid protein, Adenovirus