Coronary Revascularization in Patients Undergoing Transcatheter Aortic Valve Replacement

Can J Cardiol. 2017 Sep;33(9):1099-1109. doi: 10.1016/j.cjca.2017.03.016. Epub 2017 Mar 28.

Abstract

Concomitant coronary artery disease (CAD) is highly prevalent among patients with severe aortic stenosis (AS). Historically, surgical aortic valve replacement with coronary artery bypass grafting was the only treatment option for patients with severe AS and significant CAD. The rapid expansion of transcatheter aortic valve replacement has led to significant paradigm shifts in the treatment of severe AS and has raised new questions regarding the optimal management of CAD in these patients. We review the evidence regarding management of concomitant CAD in severe AS patients, specifically focusing on issues surrounding transcatheter aortic valve replacement. In the absence of robust evidence supporting specific treatment strategies, decisions regarding coronary revascularization in severe AS should be individualized and made within the context of a multidisciplinary heart team.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't
  • Research Support, N.I.H., Extramural

MeSH terms

  • Aortic Valve Stenosis / complications
  • Aortic Valve Stenosis / surgery*
  • Coronary Artery Disease / complications
  • Coronary Artery Disease / surgery*
  • Humans
  • Myocardial Revascularization / methods*
  • Transcatheter Aortic Valve Replacement / methods*