This first phytochemical study of leaves of Ocotea caudata led to the isolation of ten isoquinoline alkaloids, one of them previously unreported, S-(+)-9-O-demethylnorpreocoteine (1), three known flavonoids, two phenols, two eudesmane type sesquiterpenoids, one proline derivative, one fatty alcohol and a phytosterol. Their structures were elucidated on the basis of extensive 1D and 2D NMR spectroscopic analyses including HSQC, HMBC, 1H-1H COSY, NOESY, as well as HRESIMS data in addition to comparison with reports in the literature.
Keywords: Lauraceae; Ocotea caudata; aporphine alkaloids; flavonoids; phytochemicals.