Primary Melanoma of the Third Metatarsal

J Foot Ankle Surg. 2017 Nov-Dec;56(6):1292-1297. doi: 10.1053/j.jfas.2017.05.005. Epub 2017 Jun 26.

Abstract

Melanoma is a well-known malignant neoplasm of the skin, although it can also arise from other structures. Bone metastasis is not an uncommon event associated with melanoma, although primary osseous melanoma is very rare. In the present report, we describe a case of primary melanoma arising from the left third metatarsal in an adult male. The lesion was treated with surgical excision without adjunct chemotherapy, and recurrence developed approximately 12 months after the foot surgery. The patient died of the cancer 34 months after it had been identified. Primary melanoma arising in a metatarsal is rare, and we wished to highlight this unusual presentation.

Keywords: cancer; malignancy; neoplasm; rare disease.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Biopsy, Needle
  • Bone Neoplasms / diagnostic imaging
  • Bone Neoplasms / pathology*
  • Bone Neoplasms / surgery*
  • Disease Progression
  • Fatal Outcome
  • Humans
  • Immunohistochemistry
  • Magnetic Resonance Imaging / methods
  • Male
  • Melanoma / diagnostic imaging
  • Melanoma / pathology*
  • Melanoma / surgery*
  • Metatarsal Bones / diagnostic imaging
  • Metatarsal Bones / pathology*
  • Metatarsal Bones / surgery
  • Neoplasm Invasiveness / pathology
  • Neoplasm Recurrence, Local / pathology
  • Neoplasm Recurrence, Local / surgery
  • Neoplasm Staging
  • Rare Diseases
  • Risk Assessment
  • Tomography, X-Ray Computed