Copper Deficiency Myelopathy After Upper Gastrointestinal Surgery

Nutr Clin Pract. 2018 Aug;33(4):515-519. doi: 10.1177/0884533617713955. Epub 2017 Dec 14.

Abstract

A well-functioning alimentary canal is required for adequate nutrient absorption. Disruption to the upper gastrointestinal tract through surgery can lead to micronutrient malnourishment. Copper deficiency has been noted in up to 10% of those undergoing Roux-en-Y gastric bypass surgery, but sequalae are not frequently reported. The resultant deficiency states can have profound and long-term consequences if not realized early and managed appropriately. Here we present a case of copper deficiency myelopathy, a condition indistinguishable from subacute combined degeneration of the spinal cord, following upper gastrointestinal bypass surgery for gastric ulceration, further complicated by inadequate nutrition.

Keywords: bariatric surgery; copper deficiency; gastric bypass; micronutrients; myelopathy; spinal cord diseases; vitamins.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Copper / deficiency*
  • Deficiency Diseases / diagnosis*
  • Deficiency Diseases / etiology
  • Female
  • Gastric Bypass / adverse effects*
  • Humans
  • Malabsorption Syndromes / etiology*
  • Middle Aged
  • Neurodegenerative Diseases / diagnosis
  • Obesity, Morbid / surgery
  • Postoperative Complications / diagnosis*
  • Spinal Cord Diseases / diagnosis*
  • Spinal Cord Diseases / etiology

Substances

  • Copper