Objcetive: To investigate the incidence and risk factors of Lymphocele infection and the optimal timing for drainage after pelvic lymphadenectomy. Methods: This retrospective study was carried out on 397 patients who received a pelvic lymphadenectomy with or without a para-aortic lymphadenectomy between January 2009 and April 2016, due to endometrial cancer in General hospital of Tianjin medical university.A total of 76 patients developed lymphocele and 20 patients developed lymphocele infection. Results: (1)The incidence of lymphocele infection was 5.04% (20/397). Single factor analysis indicated diameter of lymphocele ≥5 cm and postoperative anemia were associated with lymphocele formation (P<0.001, P=0.023). Multiple factors Logistic analysis through the adjustment of the factors showed diameter of lymphocele ≥5 cm was the independent risk factors for lymphocyst infection (P<0.001). (2)The total treatment period of cases treated only with antibiotics tended to be shorter than that of cases treated with combined antibiotics and drainage (P=0.008). However, for severe cases which needed drainage, initiating the drainage by day 3 significantly shortened the total treatment period compared with cases started on or after day 4 (P=0.048). Conclusion: To identify the risk factors of the lymphocele infection is useful to help reduce the incidence of them with effective measurement.When drainage is required in addition to antibiotics, the earlier the drainage is performed, the shorter the treatment period is.
目的： 探讨淋巴囊肿感染发生的相关因素以及治疗淋巴囊肿的最佳引流时间。 方法： 收集2009年1月至2016年4月天津医科大学总医院妇产科行盆腔和(或)腹主动脉旁淋巴结切除的子宫内膜癌患者397例，术后发生淋巴囊肿者76例，淋巴囊肿感染者20例。 结果： (1)淋巴囊肿感染的发生率为5.04%(20/397)，经单因素分析发现淋巴囊肿直径≥5 cm ，术后贫血是淋巴囊肿感染发生的相关因素(P<0.001，P＝0.023)，多因素Logistic回归分析，发现淋巴囊肿直径≥5 cm是淋巴囊肿感染发生的独立危险因素(P＝0.000)。(2)在淋巴囊肿感染的治疗中单纯使用抗生素组较抗生素联合引流组治疗时间短(P＝0.008)。在辅以引流治疗的患者中3 d以内给予引流者治疗时间较第4天及以后给予者治疗时间缩短(P＝0.048)。 结论： 明确引起淋巴囊肿感染发生的相关因素，采取针对性预防措施，将会减少淋巴囊肿感染的发生；对于需要辅以引流治疗的患者越早给予，治疗时间将会缩短。.
Keywords: Drainage; Endometrial Cancer; Infection; Lymphocele.