Lungs in White Induced by Docetaxel

Isr Med Assoc J. 2017 Jun;19(6):393-394.

Abstract

Taxanes are often used in the treatment of many types of cancers. Side effects of docetaxel are not as well documented as paclitaxel, but both can cause pulmonary injury. We present a dramatic case of a patient being treated for prostatic adenocarcinoma with docetaxel who presented with interstitial pneumonitis and responded dramatically to the early treatment with corticosteroids. This case is important as it reveals the side effects of docetaxel administration without administration of other chemotherapeutic agents, and it illustrates the importance of early diagnosis and treatment of docetaxel-induced interstitial pneumonitis. Further research into the mechanism of the side effects of docetaxel is warranted.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Agents, Phytogenic / adverse effects*
  • Docetaxel
  • Humans
  • Lung Diseases, Interstitial / chemically induced*
  • Male
  • Paclitaxel / adverse effects
  • Taxoids / adverse effects*

Substances

  • Antineoplastic Agents, Phytogenic
  • Taxoids
  • Docetaxel
  • Paclitaxel