Rhizopus arrhizus Invasive Infection due to Self-Inflicted Scratch Injuries in a Diabetic Patient with Non-ketotic Acidosis

Mycopathologia. 2017 Oct;182(9-10):927-931. doi: 10.1007/s11046-017-0158-0. Epub 2017 Jun 23.

Abstract

Mucormycosis is a rare infection caused by members included in the subphylum Mucoromycotina. Characterized by the histopathological hallmark of angioinvasion, these infections affect most often patients with certain underlying conditions carrying immunosuppression (haematological neoplasias, diabetic ketoacidosis and other forms of acidosis, and iron overload) or immunocompetent patients with traumatic mucocutaneous barriers breakdown and direct inoculation of the mould. A case is presented in which a rare underlying condition (non-ketotic acidosis) and a rare cause of cutaneous injuries collide. Prognosis, treatment options and management decisions are described thoroughly.

Keywords: Mucormycosis; Non-ketotic acidosis; Rhizopus.

Publication types

  • Case Reports

MeSH terms

  • Acidosis / complications*
  • Adult
  • Antifungal Agents / administration & dosage
  • Debridement
  • Diabetes Complications*
  • Disease Management
  • Humans
  • Invasive Fungal Infections / diagnosis*
  • Invasive Fungal Infections / drug therapy
  • Invasive Fungal Infections / microbiology
  • Invasive Fungal Infections / pathology
  • Male
  • Mucormycosis / diagnosis*
  • Mucormycosis / drug therapy
  • Mucormycosis / microbiology
  • Mucormycosis / pathology
  • Prognosis
  • Rhizopus / classification
  • Rhizopus / isolation & purification*
  • Skin / injuries*
  • Wound Infection / complications*

Substances

  • Antifungal Agents