Diagnostic Medical Imaging in Pediatric Patients and Subsequent Cancer Risk

Acad Radiol. 2017 Nov;24(11):1456-1462. doi: 10.1016/j.acra.2017.05.009. Epub 2017 Jun 20.

Abstract

The use of diagnostic medical imaging is becoming increasingly more commonplace in the pediatric setting. However, many medical imaging modalities expose pediatric patients to ionizing radiation, which has been shown to increase the risk of cancer development in later life. This review article provides a comprehensive overview of the available data regarding the risk of cancer development following exposure to ionizing radiation from diagnostic medical imaging. Attention is paid to modalities such as computed tomography scans and fluoroscopic procedures that can expose children to radiation doses orders of magnitude higher than standard diagnostic x-rays. Ongoing studies that seek to more precisely determine the relationship of diagnostic medical radiation in children and subsequent cancer development are discussed, as well as modern strategies to better quantify this risk. Finally, as cardiovascular imaging and intervention contribute substantially to medical radiation exposure, we discuss strategies to enhance radiation safety in these areas.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Fluoroscopy / adverse effects*
  • Humans
  • Infant
  • Infant, Newborn
  • Neoplasms, Radiation-Induced / epidemiology*
  • Neoplasms, Radiation-Induced / etiology
  • Radiation Dosage
  • Radiation, Ionizing*
  • Risk Assessment
  • Risk Factors
  • Tomography, X-Ray Computed / adverse effects*
  • Young Adult