Mussel-inspired nano-multilayered coating on magnesium alloys for enhanced corrosion resistance and antibacterial property

Colloids Surf B Biointerfaces. 2017 Sep 1:157:432-439. doi: 10.1016/j.colsurfb.2017.06.013. Epub 2017 Jun 17.

Abstract

Magnesium alloys are promising candidates for load-bearing orthopedic implants due to their biodegradability and mechanical resemblance to natural bone tissue. However, the high degradation rate and the risk of implant-associated infections pose grand challenges for their clinical applications. Herein, we developed a nano-multilayered coating strategy through polydopamine and chitosan assisted layer-by-layer assembly of osteoinductive carbonated apatite and antibacterial sliver nanoparticles on the surface of AZ31 magnesium alloys. The fabricated nano-multilayered coating can not only obviously enhance the corrosion resistance but also significantly increase the antibacterial activity and demonstrate better biocompatility of magnesium alloys.

Keywords: Antibacterial; Carbonated apatite; Magnesium alloy; Polydopamine; Sliver.

MeSH terms

  • Alloys / chemistry*
  • Animals
  • Anti-Bacterial Agents / chemistry*
  • Bivalvia
  • Indoles / chemistry
  • Magnesium / chemistry*
  • Polymers / chemistry
  • Silver / chemistry

Substances

  • Alloys
  • Anti-Bacterial Agents
  • Indoles
  • Polymers
  • polydopamine
  • Silver
  • Magnesium