Gibberellic and kaurenoic hybrid strigolactone mimics for seed germination of parasitic weeds

Pest Manag Sci. 2017 Dec;73(12):2529-2537. doi: 10.1002/ps.4650. Epub 2017 Aug 18.

Abstract

Background: Parasitic weeds are widespread and cause significant losses in important crops. Their germination requires the detection of crop-derived molecules such as strigolactones. Strigolactone mimics are germination-inducing molecules with the potential to apply a suicidal germination strategy for seed bank control of parasitic weeds.

Results: The D-ring, which is instrumental in the germination process of seeds of parasitic weeds, was attached to gibberellin (GA3 ) and kaurenoic acid as the scaffold. It was shown that indeed strigolactone mimics prepared from GA3 and kaurenoic acid are active as stimulants when a D-ring is present; some of the mimics are as active as GR24.

Conclusions: The starting molecules were plant hormones that had previous growth-regulating activity in other organisms and the products showed enhanced activity towards parasitic weeds. The information generated may contribute to a better understanding of the germination biochemistry of the weed species used. Further research is required in this area but it is clear that the results are promising. © 2017 Society of Chemical Industry.

Keywords: broomrape; gibberellins; grandiflorenic acid; kaurenoic acid; suicidal germination; witchweed.

MeSH terms

  • Diterpenes / chemistry
  • Diterpenes / pharmacology*
  • Germination
  • Gibberellins / chemistry
  • Gibberellins / pharmacology*
  • Molecular Structure
  • Plant Growth Regulators / chemistry
  • Plant Growth Regulators / pharmacology*
  • Plant Weeds / drug effects*
  • Plant Weeds / growth & development
  • Seeds / drug effects
  • Seeds / growth & development*

Substances

  • Diterpenes
  • Gibberellins
  • Plant Growth Regulators
  • kaurenoic acid