Malignant Syndrome or Withdrawal Reaction?

Shanghai Arch Psychiatry. 2016 Aug 25;28(4):227-229. doi: 10.11919/j.issn.1002-0829.216048.

Abstract

We report on a case of a female patient who had serious side effects from treatment with clozapine and chlorpromazine and the appeared to have a withdrawal reaction from cessation of clozapine. During the treatment process she was misdiagnosed as having malignant syndrome. This case highlights the importance of clinicians being able to distinguish malignant syndrome from withdrawal reactions, and to be familiar with treatment and prevention methods for both.

我们报告一名女性患者在抗精神病药物过程中 使用氯氮平和氯丙嗪出现严重的不良反应,随后患者 氯氮平的突然停药后出现撤药反应。在处理过程中曾 误诊为恶性综合征,因此临床医生需要识别恶性综合 征及撤药反应,熟悉处理及预防方法。.

Keywords: clozapine; malignant syndrome; schizophrenia; withdrawal reaction.

Publication types

  • Case Reports