Centrosome Assembly: Reconstructing the Core Cartwheel Structure In Vitro

Gaëlle Marteil; Marco António Dias Louro; Mónica Bettencourt-Dias

doi:10.1016/j.cub.2017.04.044

Centrosome Assembly: Reconstructing the Core Cartwheel Structure In Vitro

Curr Biol. 2017 Jun 19;27(12):R606-R609. doi: 10.1016/j.cub.2017.04.044.

Authors

Gaëlle Marteil¹, Marco António Dias Louro², Mónica Bettencourt-Dias³

Affiliations

¹ Instituto Gulbenkian de Ciência, Oeiras, 2780-156, Portugal. Electronic address: gmarteil@igc.gulbenkian.pt.
² Instituto Gulbenkian de Ciência, Oeiras, 2780-156, Portugal.
³ Instituto Gulbenkian de Ciência, Oeiras, 2780-156, Portugal. Electronic address: mdias@igc.gulbenkian.pt.

PMID: 28633033
DOI: 10.1016/j.cub.2017.04.044

Abstract

Centrioles are microtubule-based cylinders essential for the formation of centrosomes and cilia. A recent study provides a new cell-free assay that reconstitutes the initial structure formed during centriole assembly - the cartwheel - and proposes a new model for its formation and growth.

Publication types

Comment

MeSH terms

Centrioles*
Centrosome*
Cilia
Microtubules