Accuracy of J-CTO Score Derived From Computed Tomography Versus Angiography to Predict Successful Percutaneous Coronary Intervention

JACC Cardiovasc Imaging. 2018 Feb;11(2 Pt 1):209-217. doi: 10.1016/j.jcmg.2017.01.028. Epub 2017 Jun 14.

Abstract

Objectives: The aim of this study was to compare the ability of conventional versus computed tomography angiography (CTA) to predict procedural success and 30-min wire crossing rates in percutaneous coronary intervention (PCI) for chronic total occlusion (CTO) lesions.

Background: Coronary CTA can be used to assess the morphology of CTO lesions.

Methods: We examined 205 consecutive patients (218 CTO lesions) who underwent coronary CTA pre-PCI. The J-CTO (Multicenter CTO Registry of Japan) score (the sum of the following 5 binary parameters: blunt proximal cap, calcification, bending >45°, and length of occluded segment >20 mm plus previously failed PCI attempt) was calculated using both CTA and conventional coronary angiography and compared.

Results: The median patient age was 69 years (interquartile range: 62 to 75 years), 82.4% were male, and a retrograde approach was attempted in 72 (33.0%) cases. The procedural success rate of the CTO-PCI procedures was 82.6%, and 29.4% of cases achieved 30-min wire crossing. The areas under the curve of the CTA-derived J-CTO score for predicting procedural success and 30-min wire crossing were significantly greater than those derived from conventional angiography (0.855 vs. 0.698; p < 0.001 for procedural success and 0.812 vs. 0.692; p < 0.001, for 30-min wire crossing). In addition, the areas under the curve of CTA-derived evaluations of calcification, bending, and occlusion length were significantly higher than those of derived from angiography for predicting procedural success.

Conclusions: The CTA-derived J-CTO score was a more useful predictor of both procedural success and 30-min wire crossing than the J-CTO score derived from conventional angiography.

Keywords: chronic total occlusion; computed tomography; coronary angiography; percutaneous coronary intervention.

Publication types

  • Comparative Study
  • Observational Study

MeSH terms

  • Aged
  • Chronic Disease
  • Computed Tomography Angiography*
  • Coronary Angiography / methods*
  • Coronary Occlusion / diagnostic imaging*
  • Coronary Occlusion / therapy*
  • Coronary Vessels / diagnostic imaging*
  • Female
  • Humans
  • Japan
  • Male
  • Middle Aged
  • Observer Variation
  • Percutaneous Coronary Intervention* / adverse effects
  • Predictive Value of Tests
  • Reproducibility of Results
  • Retrospective Studies
  • Treatment Outcome
  • Vascular Calcification / diagnostic imaging
  • Vascular Calcification / therapy