DAMed in (Trem) 2 Steps

Sandro Da Mesquita; Jonathan Kipnis

doi:10.1016/j.cell.2017.05.039

DAMed in (Trem) 2 Steps

Cell. 2017 Jun 15;169(7):1172-1174. doi: 10.1016/j.cell.2017.05.039.

Authors

Sandro Da Mesquita¹, Jonathan Kipnis²

Affiliations

¹ Center for Brain Immunology and Glia, Department of Neuroscience, School of Medicine, University of Virginia, Charlottesville, VA 22908, USA.
² Center for Brain Immunology and Glia, Department of Neuroscience, School of Medicine, University of Virginia, Charlottesville, VA 22908, USA. Electronic address: kipnis@virginia.edu.

PMID: 28622503
DOI: 10.1016/j.cell.2017.05.039

Abstract

The role of microglia in neurodegenerative diseases has been controversial. In this issue, Keren-Shaul et al. identify a unique population of disease-associated microglia (DAM) that develop in two steps and may help to restrict damage in Alzheimer and related diseases.

Publication types

Comment

MeSH terms

Humans
Microglia*
Neurodegenerative Diseases*