Acute lymphoblastic leukemia cells create a leukemic niche without affecting the CXCR4/CXCL12 axis

Haematologica. 2017 Oct;102(10):e389-e393. doi: 10.3324/haematol.2016.159517. Epub 2017 Jun 15.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cell Movement
  • Cells, Cultured
  • Chemokine CXCL12 / metabolism*
  • Coculture Techniques
  • Humans
  • Mesenchymal Stem Cells / pathology
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / pathology*
  • Receptors, CXCR4 / metabolism*

Substances

  • CXCL12 protein, human
  • CXCR4 protein, human
  • Chemokine CXCL12
  • Receptors, CXCR4