Bioelements in hair of children with selected neurological disorders

Acta Biochim Pol. 2017;64(2):279-285. doi: 10.18388/abp.2016_1380. Epub 2017 Jun 14.

Abstract

We have analyzed concentrations of magnesium (Mg), calcium (Ca), copper (Cu), zinc (Zn) and iron (Fe) in hair of a group of 82 children with mental retardation, in which 9 patients suffered from epilepsy, 18 from the Down's syndrome and 55 from cerebral palsy. Girls comprised little over 50% of the patients. In the group of boys with epilepsy, we found Mg, Ca, Cu and Fe deficiency, and normal level of Zn. In the group of girls with epilepsy, apart from low Fe concentration, a high level of Ca, Mg, Zn, and Cu was noted. For girls with the Down's syndrome, a high or normal level of Ca, Mg, Zn and Cu was found, whereas the Fe concentration varied and presented itself in a non-characteristic way. Both groups of children with cerebral palsy, i.e. boys and girls, displayed low Fe concentration in their hair; low Cu level was found in older patients as well. In this group of patients, we also noted high concentrations of Ca, Mg and Zn in girls and normal in boys. A high concentration of Ca in girls with cerebral palsy requires separate analysis. The obtained results could be useful as guidance in the direction and determination of the amount of possible patient nutritional supplementation.

Keywords: Down's syndrome; bioelements; cerebral palsy; children; epilepsy; hair.

MeSH terms

  • Adolescent
  • Calcium / metabolism
  • Cerebral Palsy / metabolism*
  • Cerebral Palsy / pathology
  • Child
  • Child, Preschool
  • Copper / metabolism
  • Dietary Supplements
  • Down Syndrome / metabolism*
  • Down Syndrome / pathology
  • Epilepsy / metabolism*
  • Epilepsy / pathology
  • Female
  • Hair / metabolism
  • Humans
  • Intellectual Disability / metabolism*
  • Intellectual Disability / pathology
  • Iron / metabolism
  • Magnesium / metabolism
  • Male
  • Sex Characteristics
  • Trace Elements / metabolism*
  • Young Adult
  • Zinc / metabolism

Substances

  • Trace Elements
  • Copper
  • Iron
  • Magnesium
  • Zinc
  • Calcium